Estimating EQ-5D health states values for Rheumatoid Arthritis patients: a limited dependent variable, mixture modelling approach (2012)
MÓNICA HERNÁNDEZ ALAVA
Allan Wailoo
10.15131/shef.data.11902848.v2
https://orda.shef.ac.uk/articles/poster/Estimating_EQ-5D_health_states_values_for_Rheumatoid_Arthritis_patients_a_limited_dependent_variable_mixture_modelling_approach/11902848
<p>• Clinical trials often do not contain preference based outcome
measure</p>
<p>• Cost per QALY evaluation requires such outcomes</p>
<p>• Linking clinical to preference based outcomes via statistical
model is commonplace in economic evaluation</p>
<p>• 22% of NICE appraisals include “mapping”, 100% in RA</p>
<p>• Typically done using simple regression techniques </p>
<p>• EQ-5D has an odd distribution </p>
<p>• Standard methods perform badly</p>
<p>• Develop and refine a new method here</p>
<p> </p>
2020-02-28 11:48:19
Rheumatoid arthritis
statistical model
clinical trials
Health Economics