Estimating EQ-5D health states values for Rheumatoid Arthritis patients: a limited dependent variable, mixture modelling approach (2012) MÓNICA HERNÁNDEZ ALAVA Allan Wailoo 10.15131/shef.data.11902848.v2 https://orda.shef.ac.uk/articles/poster/Estimating_EQ-5D_health_states_values_for_Rheumatoid_Arthritis_patients_a_limited_dependent_variable_mixture_modelling_approach/11902848 <p>• Clinical trials often do not contain preference based outcome measure</p> <p>• Cost per QALY evaluation requires such outcomes</p> <p>• Linking clinical to preference based outcomes via statistical model is commonplace in economic evaluation</p> <p>• 22% of NICE appraisals include “mapping”, 100% in RA</p> <p>• Typically done using simple regression techniques </p> <p>• EQ-5D has an odd distribution </p> <p>• Standard methods perform badly</p> <p>• Develop and refine a new method here</p> <p> </p> 2020-02-28 11:48:19 Rheumatoid arthritis statistical model clinical trials Health Economics