Clinical effectiveness of bisphosphonates for prevention of fragility fractures: a systematic review and network meta-analysis
2020-03-09T16:20:37Z (GMT) by
BACKGROUND Osteoporosis is characterised by low bone mass and structural deterioration of bone tissue, with a consequent increase in susceptibility to fragility fracture. Fractures cause significant pain, disability and loss of independence and can be fatal.  OBJECTIVE To assess the relative efficacy of bisphosphonates (alendronate, risedronate, ibandronate and zoledronate) for the treatment of Osteoporosis using a network meta-analysis (NMA).