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Microarray data for "MYT1L mutations cause intellectual disability and variable obesity by dysregulating gene expression and development of the neuroendocrine hypothalamus"

dataset
posted on 20.04.2021, 19:41 by Alisdair McNeillAlisdair McNeill
Organism: Human Embryonic (HEK) line
samples: 3 x CRISPR Knockout HEK line cultures and 3x isogenic wild type HEK cell cultures
Array: Clarion S array (Thermofisher)
Experiment: whole genome gene expression profiling in MYT1L null HEK cell lines (generated by CRISPR) and 3 x isogenic wild type HEK cell lines.

Protocol provided in "MYT1L mutations cause intellectual disability and variable obesity by dysregulating gene expression and development of the neuroendocrine hypothalamus" Published in PLoS Genetics, 13 (8). e1006957. ISSN 1553-7390 DOI: 10.1371/journal.pgen.1006957


"C" files are from isogenic controls.
"21481" files are from MYT1L null cells

Funding

BDF Newlife SG/15-16/07

History

Ethics

There is no personal data or any that requires ethical approval

Policy

The data complies with the institution and funders' policies on access and sharing

Sharing and access restrictions

The data can be shared openly

Data description

  • The file formats are open or commonly used

Methodology, headings and units

  • Headings and units are explained in the files