Microarray data for "MYT1L mutations cause intellectual disability and variable obesity by dysregulating gene expression and development of the neuroendocrine hypothalamus"
Organism: Human Embryonic (HEK) line
samples: 3 x CRISPR Knockout HEK line cultures and 3x isogenic wild type HEK cell cultures
Array: Clarion S array (Thermofisher)
Experiment: whole genome gene expression profiling in MYT1L null HEK cell lines (generated by CRISPR) and 3 x isogenic wild type HEK cell lines.
Protocol provided in "MYT1L mutations cause intellectual disability and variable obesity by dysregulating gene expression and development of the neuroendocrine hypothalamus" Published in PLoS Genetics, 13 (8). e1006957. ISSN 1553-7390 DOI: 10.1371/journal.pgen.1006957
"C" files are from isogenic controls.
"21481" files are from MYT1L null cells
Funding
BDF Newlife SG/15-16/07
History
Ethics
There is no personal data or any that requires ethical approvalPolicy
The data complies with the institution and funders' policies on access and sharingSharing and access restrictions
The data can be shared openlyData description
- The file formats are open or commonly used
Methodology, headings and units
- Headings and units are explained in the files
CC BY 4.0