The University of Sheffield
time_CDM uptake in MDA-MB-231 cells.avi (365.84 kB)
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MDA-MB-231 cells internalising CDM

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posted on 2023-06-21, 17:15 authored by Montserrat Llanses Martinez

Video associated with the PhD Thesis entitled " Dissecting Extracellular Matrix Internalisation Mechanisms using Functional Genomics", Chapter 6, Figure 6-23.  To assess whether MDA-MB-231 cells internalise ECM during cell migration, cell derived matrices (CDM) were labelled with pHrodo, a pH sensitive dye. Cell imaging was performed every 10 minutes. Time-lapse visualisation indicated that MDA-MB-231 cells were able to internalise CDM as they migrated. 



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