Estimating EQ-5D health states values for Rheumatoid Arthritis patients a limited dependent variable, mixture modelling approach 2012.ppt (416.5 kB)
Download fileEstimating EQ-5D health states values for Rheumatoid Arthritis patients: a limited dependent variable, mixture modelling approach (2012)
• Clinical trials often do not contain preference based outcome measure
• Cost per QALY evaluation requires such outcomes
• Linking clinical to preference based outcomes via statistical model is commonplace in economic evaluation
• 22% of NICE appraisals include “mapping”, 100% in RA
• Typically done using simple regression techniques
• EQ-5D has an odd distribution
• Standard methods perform badly
• Develop and refine a new method here
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