Estimating EQ-5D health states values for Rheumatoid Arthritis patients a limited dependent variable, mixture modelling approach 2012.ppt (416.5 kB)

Estimating EQ-5D health states values for Rheumatoid Arthritis patients: a limited dependent variable, mixture modelling approach (2012)

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posted on 28.02.2020, 11:48 by MÓNICA HERNÁNDEZ ALAVA, Allan Wailoo

• Clinical trials often do not contain preference based outcome measure

• Cost per QALY evaluation requires such outcomes

• Linking clinical to preference based outcomes via statistical model is commonplace in economic evaluation

• 22% of NICE appraisals include “mapping”, 100% in RA

• Typically done using simple regression techniques

• EQ-5D has an odd distribution

• Standard methods perform badly

• Develop and refine a new method here

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