Exploratory psychometric analysis of the EQ-5D in a Myelofibrosis population (ISPOR 20th Annual International Meeting 16-20 May 2015)
posterposted on 27.02.2020 by Rachid Rafia, Clara Mukuria
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The EQ-5D is a generic preference-based measure of health-related quality of life (HRQoL) applicable to a wide range of health conditions and treatments.1 Myelofibrosis (MF) is a rare but serious bone-marrow cancer in which the proliferation of an abnormal type of bone marrow stem cell results in fibrosis, or the replacement of the marrow with collagenous connective tissue fibres. Massive spleen enlargement is a consequence of the resulting extra-medullary haematopoiesis and can cause symptoms (typically abdominal pain, early satiety and difficulty in breathing); and can lead to complications such as portal hypertension, splenic infarction and vascular events. Patients commonly have symptoms such as fever, night sweats, and weight loss.
There is no evidence about the appropriateness of the EQ-5D in MF; thus, this study aimed to provide psychometric evidence of its appropriateness.
EthicsThere is no personal data or any that requires ethical approval
PolicyThe data complies with the institution and funders' policies on access and sharing
Sharing and access restrictionsThe data can be shared openly
- The file formats are open or commonly used
Methodology, headings and units
- Headings and units are explained in the files