Prognostic accuracy of Exercise ECG and CT Coronary Angiography to predict Major Adverse Cardiac Events (MACE) in patients with suspected Acute Coronary Syndrome (ACS): A systematic review (2012)

Acute coronary syndrome (ACS) typically occurs when a patient with coronary artery disease (CAD) develops an obstruction in their coronary arteries. Chest pain is responsible for 700,000 admissions to Emergency Departments (ED) per year in England and Wales. The differentiation of ACS from other non-cardiac causes of chest pain can present a challenge. Inappropriate discharge of high risk patients to cardiac wards. Therefore accurate risk stratification is important for patients presenting with suspected ACS.

Whilst exercise ECG and CT coronary angiography (CTCA) are both tools commonly used to assess patients stable symptoms due to CAD, they are less commonly used in the risk stratification of patients presenting to the ED with suspected ACS.